Vilka hormoner behövs för spermatogenesen?
Testosteronet som testikeln utsöndrar behövs för att puberteten ska börja, de manliga könsegenskaperna ska utformas och spermier produceras. Spermieproduktionen, spermatogenesen, (bild ovan) sker i de långa sädeskanalerna i testiklarna.
Hur regleras spermatogenesen?
Reglering av spermatogenesen: *Hormonet som reglerar spermatogenesen kallas Inhibin. -inhibin hämmar frisättning av FSH från adenohypofysen. -Detta utsöndras lite hela tiden, vilket gör att det ligger en konstant broms på spermatogenesen som då håller sig på en viss nivå (kroppen vill alltid producera spermier).
How do FSH and LH regulate spermatogenesis?
Both FSH (directly) and LH (indirectly via testosterone-androgen receptor [AR]) exert their actions on spermatogenesis mainly through the regulation of Sertoli cell factors. In response to the gonadotropins, 2 major endocrine signals are produced from the testis.
Which hormones are involved in spermatogenesis?
Hormonal control of spermatogenesis varies among species. The initiation of spermatogenesis occurs at the onset of puberty due to the interactions of the hypothalamus, pituitary gland, and Sertoli and Leydig cells. If the pituitary gland is removed, spermatogenesis can still be initiated by follicle-stimulating hormone (FSH) and testosterone.
What is spermatogenesis?
Spermatogenesis is a concerted sequence of events during maturation of spermatogonia into spermatozoa. The process involves differential gene-expression and cell-cell interplay regulated by the key endocrine stimuli, i.e., follicle-stimulating hormone (FSH) and luteinizing hormone (LH)-stimulated testosterone.
How do you stimulate spermatogenesis in hypogonadism?
Spermatogenesis Stimulation. The induction of spermatogenesis in patients with hypogonadotropic hypogonadism requires testicular stimulation with GnRH or gonadotropins. Various preparations are available (see Table 1) to reach this goal, each with advantages and disadvantages.