What is hydroxyzine?

What is hydroxyzine?

What is hydroxyzine? Hydroxyzine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin. Hydroxyzine may be used to treat allergic skin reactions such as hives or contact dermatitis.

How does hydroxyzine cross the blood–brain barrier?

Hydroxyzine crosses the blood–brain barrier easily and exerts effects in the central nervous system. A positron emission tomography (PET) study found that brain occupancy of the H 1 receptor was 67.6% for a single 30 mg dose of hydroxyzine.

What is Atarax (verify) hydroxyzine?

(verify) Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is a first-generation antihistamine. It was first synthesized by Union Chimique Belge in 1956 and was marketed by Pfizer in the United States later the same year and is still widely used today.

How is hydroxyzine synthesized from piperazine?

Hydroxyzine is synthesized by the alkylation of 1- (4-chlorobenzhydryl)piperazine with 2- (2-chloroethoxy)ethanol: Hydroxyzine preparations require a doctor’s prescription.

Hydroxyzine is in a class of medications called antihistamines. It works by blocking the action of histamine a substance in the body that causes allergic symptoms. It also works by decreasing activity in the brain. How should this medicine be used? Hydroxyzine comes as capsules, tablets, a syrup, and suspension to take by mouth.

How do I know when to stop taking hydroxyzine?

Stop using hydroxyzine and call your doctor at once if you have: fast or pounding heartbeats; headache with chest pain; severe dizziness, fainting; or a seizure (convulsions).

What happens if you drink alcohol with hydroxyzine?

Drinking alcohol with this medicine can cause side effects. Get emergency medical help if you have signs of an allergic reaction to hydroxyzine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. In rare cases, hydroxyzine may cause a severe skin reaction.

What does hydroxyzine do to histamine?

It also acts as an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin. Hydroxyzine is used as a sedative to treat anxiety and tension.

How much hydroxyzine is safe to take for anxiety?

Although hydroxyzine is an antihistamine, people also use it to manage many different types of anxiety disorders, including generalized anxiety disorder (GAD). For symptomatic relief of anxiety and tension, the recommended dose for adults is 50 to 100 mg four times a day. Children under 6 years of age can take 50 mg daily in divided doses.

How do you measure hydroxyzine?

Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Hydroxyzine is for short-term use only.

Can hydroxyzine cause a serious heart problem?

Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Tell your doctor about all medicines you use,…

What happens if you take too much hydroxyzine?

In rare cases, hydroxyzine may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have sudden skin redness or a rash that spreads and causes white or yellow pustules, blistering, or peeling. Stop using hydroxyzine and call your doctor at once if you have: a seizure (convulsions).

When should I stop taking hydroxyzine?

Stop using hydroxyzine and call your doctor at once if you have: 1 fast or pounding heartbeats; 2 headache with chest pain; 3 severe dizziness, fainting; or 4 a seizure (convulsions). More

How much does hydroxyzine cost in the UK?

In the United Kingdom 28 doses cost less than a pound. In the United States the wholesale cost in 2018 was about 0.05 USD per dose. In the United States about 8 million prescriptions were written for hydroxyzine in 2016.

Can hydroxyzine be used for motion sickness?

(verify) Hydroxyzine, sold under the brand names Atarax among others, is a medication of the antihistamine type. It is used in the treatment of itchiness, anxiety, and nausea, including that due to motion sickness.

What happens when you stop taking hydroxyzine?

Stop taking this medicine and call your doctor right away if you have sudden skin redness or a rash that spreads and causes white or yellow pustules, blistering, or peeling. Stop using hydroxyzine and call your doctor at once if you have: a seizure (convulsions). Side effects such as drowsiness and confusion may be more likely in older adults.

How long does hydroxyzine take to work?

Response and Effectiveness Hydroxyzine is rapidly absorbed from the gastrointestinal tract and its clinical effects are usually apparent within 15 to 30 minutes after oral administration. 7. Interactions

How long can you take hydroxyzine for anxiety?

If you do not have a dose-measuring device, ask your pharmacist for one. Hydroxyzine is for short-term use only. You should not take this medicine for longer than 4 months. Call your doctor if your anxiety symptoms do not improve, or if they get worse.

Does Ambien interact with hydroxyzine?

Hydroxyzine interactions with Ambien produce a moderate drug interaction with profound drowsiness, difficulty concentrating, slow coordination, and impaired judgment. A combination of these two drugs and alcohol will only potentiate the sedative effect on CNS.

Can you drink alcohol while taking hydroxyzine?

Hydroxyzine interactions with alcohol is considered a food-drug interaction. According to a study, Vistaril is not a depressant, and its use leads to sedative effects due to the suppression activity of the drug in the central nervous system.

What are the risks of taking NSAIDs?

NSAIDs can increase your risk of a fatal heart attack or stroke. The risk increases the higher the dosage and the longer the length of time you remain on an NSAID for. People with pre-existing heart disease are more at risk and certain NSAIDs, such as diclofenac and celecoxib, have been linked to more heart-related side effects than others.

What is the brand name for hydroxyzine pamoate?

Hydroxyzine -name brands:Anxanil, Atarax, Vistaril, Hydroxyzine Pamoate. Type of Drug: Sedative -antihistamine. prescribed for-nausea and vomiting, reducing emotional stress(such as anxiety,tension,agitation)