Innehållsförteckning
Är neuropati vanligt?
Snabba fakta om polyneuropati Polyneuropati är vanligt och kan bero på antingen ärftliga faktorer eller på andra sjukdomar (exempelvis diabetes). Men hos många är orsaken okänd, och då kallas polyneuropatin för idiopatisk i dessa fall. Förloppet kan vara akut eller utdraget under lång tid.
Varför snubblar man?
Snubblar och snavar gör vi alla när vi är ouppmärksamma. Men förmågan att hantera den uppkomna situationen varierar beroende på hur bra balans vi har. Det är till stor del reflexstyrda reaktioner i nervsystem och muskler som avgör om en människa snabbt återfår kontrollen eller faller handlöst.
How does chlorambucil affect the body?
Chlorambucil can cause a decrease in the number of blood cells in your bone marrow. Your doctor will order laboratory tests before, during, and after your treatment to see if your blood cells are affected by this drug. Keep all appointments with the laboratory. Chlorambucil may increase the risk that you will develop other cancers.
What type of cancer is chlorambucil used to treat?
Chlorambucil is also used to treat non-Hodgkin’s lymphoma (NHL) and Hodgkin’s disease (types of cancer that begin in certain white blood cells that normally fight infection). Chlorambucil is in a class of medications called alkylating agents.
What is the best way to take chlorambucil?
Take chlorambucil at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take chlorambucil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
What are the limitations to bioavailability of chlorambucil?
Limitations to bioavailability. This is important since chlorambucil, as an electrophile, is made less reactive by conjugation with glutathione, thereby making the drug less toxic to the cell. Shown above, chlorambucil reacts with glutathione as catalyzed by hGSTA 1-1 leading to the formation of the monoglutathionyl derivative of chlorambucil.