När använder man acetylsalicylsyra?
Febernedsättningen beror på att acetylsalicylsyra ökar kroppens värmeavgivning. Acetylsalicylsyra Abece används vid tillfälliga lätta till måttliga smärttillstånd, t. ex. mot huvudvärk, tandvärk, muskel- och ledvärk, menstruationssmärtor samt vid feber vid förkylningssjukdomar.
Kan man ta aspirin och Alvedon?
Svaret är att du aldrig ska blanda läkemedel utan att först rådgöra med en läkare eller fråga en farmaceut. En läkare kan i vissa tillfällen ordinera dig att kombinera vissa sorters värktabletter, medan det kan vara särskilt farligt att kombinera andra.
Is paracetamol efikasan?
Svjetska zdravstvena organizacija (WHO) preporučuje da se paracetamol koristi samo za ublažavanje groznice kod djece ako je njihova tjelesna temperatura veća od 38,5 °C. Efikasnost paracetamola samog po sebi kod djece s groznicom je upitna, a meta-analiza je pokazala da je manje efikasan od ibuprofena.
Is Phenacetin a metabolite of paracetamol?
Since a major portion of a dose of phenacetin is rapidly metabolised to paracetamol, it seems possible that phenacetin owes some of its therapeutic activity to its main metabolite, paracetamol, whereas its most troublesome side effect (methaemoglobinaemia) is due to another metabolite, p-phenetidine.
What are the classical methods for the production of paracetamol?
The classical methods for the production of paracetamol involve the acetylation of 4-aminophenol with acetic anhydride as the last step. They differ in how 4-aminophenol is prepared. In one method, nitration of phenol with nitric acid affords 4-nitrophenol, which is reduced to 4-aminophenol by hydrogenation over Raney nickel.
Is paracetamol a metabolite of acetanilide?
In 1948, Bernard Brodie, Julius Axelrod and Frederick Flinn confirmed that paracetamol was the major metabolite of acetanilide in humans, and established that it was just as efficacious an analgesic as its precursor. They also suggested that methemoglobinemia is produced in humans mainly by another metabolite, phenylhydroxylamine.